Clarissa Brincat

All articles by Clarissa Brincat

• New review highlights need for proactive care in SM-related bone disease

  In systemic mastocytosis, mast cells release substances that disturb the normal balance of bone health and can lead to osteoporosis.

• Blood enzyme spike during anaphylaxis may reveal hidden SM

  Measuring levels of a chemical in the blood called diamine oxidase during anaphylaxis could help doctors diagnose patients with hidden SM.

• New trial seeks to learn more about indolent SM

  A new clinical trial published on ClinicalTrials.gov is underway to better understand how indolent SM affects people and how it is managed. 

• SM associated with greater flare severity than CM

  Systemic mastocytosis (SM) is associated with more severe symptom flares than cutaneous mastocytosis (CM), according to a recent study.

• Study identifies previously unknown side effects from epinephrine

  A recent study identified previously unknown side effects from epinephrine, a treatment carried by many with SM.

• Indolent systemic mastocytosis may speed up aging

  Indolent SM may cause the body to age faster than normal, according to a recent study published in the journal Innovation in Aging.

• Mastocytosis increases risk of serious reactions to insect stings

  There is a strong link between mastocytosis and serious allergic reactions to insect stings, especially from insects like bees and wasps.

• Review explores signs and treatment of SM in children

  When children develop small, uniform reddish-brown spots or bumps on their back, belly, or limbs, it may be a sign of SM.

• Mast cells contribute to anemia in SM, study finds

  In people with SM, mast cells may contribute to anemia by breaking down red blood cells.

• New data indicates bezuclastinib may slow down SM

  Results from a phase 2 clinical trial suggest bezuclastinib may help treat the underlying cause of nonadvanced SM, as well as its symptoms.