News

Waking during the night was common: 88% of patients with ISM had interrupted sleep.

Many patients with SM start with basal serum tryptase levels below the diagnostic threshold, but these levels often increase with time.

A small study comparing those with SM-AHN to other patients with SM uncovered several differences that may guide diagnosis and care.

A phase 2 trial will test if modifying donor stem cells can reduce GVHD after stem cell transplant for blood cancers, including MCL.

The test can detect the KIT D816V mutation even when it is present in fewer than one in 100,000 copies of the genetic material tested.

A woman developed a subtype that was especially rare: unlike most adult mastocytosis cases she had large, irregular skin spots and no signs of SM.

Epinephrine auto-injector shelf life averaged 12.8 months in Canadian pharmacies, compared with 19–24 months at manufacturing release.

A pattern showing both normal and abnormal mast cells was more common in less aggressive forms of clonal mast cell disease.

A 75-year-old man with recurrent hip fractures was diagnosed with mast cell leukemia after imaging revealed suspicious bone lesions.

The FDA has accepted Cogent Biosciences’ application for bezuclastinib in the treatment of advanced SM, with a decision expected in 2027.