Researchers link mast cell patterns to disease severity
A pattern showing both normal and abnormal mast cells was more common in less aggressive forms of clonal mast cell disease.
A pattern showing both normal and abnormal mast cells was more common in less aggressive forms of clonal mast cell disease.
A 75-year-old man with recurrent hip fractures was diagnosed with mast cell leukemia after imaging revealed suspicious bone lesions.
The FDA has accepted Cogent Biosciences’ application for bezuclastinib in the treatment of advanced SM, with a decision expected in 2027.
Barzolvolimab reduced allergy-type activation of mast cells with the KIT D816V mutation in SM, a lab study found.
Clonal mast cell disease, including SM, may be more common in patients with anaphylaxis than previously recognized.
A man with SM-AHN and primary myelofibrosis developed multiorgan failure following a suspected splenic rupture.
The recall refers to multidose vials used in healthcare settings, not the epinephrine autoinjectors patients with SM likely have at home.
People with Hymenoptera venom allergy who take cholesterol-lowering drugs may have twice the odds of a severe sting reaction, a study found.
Allogeneic hematopoietic cell transplantation improved overall survival among individuals with SM with an associated acute myeloid leukemia.
An ultrasensitive test for SM found higher levels of the KIT mutation in bone marrow than blood and linked mutation levels with severity.