Ariana Boswell

All articles by Ariana Boswell

• Case report: Aortic valve replacement failure in patient with aggressive SM

  A case report describes a patient who experienced two failed transcatheter aortic valve replacements, likely related to her underlying SM.

• Duplex sequencing uncovers additional responders to avapritinib

  Duplex sequencing can reveal KIT mutations in a subset of patients with SM who do not have detectable mutations by ddPCR, a study found.

• Rare Disease Day: Why it matters and how to get involved

  Rare Disease Day 2025 aims to uplift the rare disease community and promote greater awareness.

• Case report: Patient with SM undergoes successful thyroidectomy

  A recent case report illustrated the need for thorough care to prevent adverse postoperative outcomes in patients with SM.

• Case report highlights complexity of diagnosing SM in children

  A case study illustrated the difficulty of diagnosing systemic mastocytosis (SM), particularly in children.

• Clinical trial to assess long-term safety of avapritinib to treat SM

  A new study is recruiting participants and will evaluate the safety of avapritinib in treating SM over a period of four years.

• SM and myeloproliferative neoplasms: Similarities and differences

  SM was once considered a subclass of myeloproliferative neoplasms, but that’s changed. Still, there is overlap between them.

• More sensitive techniques recommended to detect SM mutations

  A new review recommended the use of sensitive mutation detection methods to better diagnose systemic mastocytosis (SM).