Ariana Boswell

All articles by Ariana Boswell

• What is the WHO classification for systemic mastocytosis subtypes?

  The WHO guidelines provide a standardized framework that helps doctors provide the right care for patients.

• New test may improve detection of KIT mutations

  Flow-SuperRCA is a new, ultra-sensitive test to detect the D816V KIT mutation in patients with SM and other mast cell conditions.

• Drug reactions in SM may be less common than previously thought

  Drug-induced reactions such as anaphylaxis are possible in patients with SM, but recent data suggests that the risk is relatively low.

• Advancements in flow cytometry may improve SM diagnosis

  A combination of quantitative and laboratory techniques may be used to improve the diagnosis of SM with flow cytometry, a recent study found.

• Clinical trial examining cancer drug TL-895 for indolent systemic mastocytosis

  A clinical trial is currently underway to determine the optimal dosage of a novel cancer drug in patients with ISM.

• New study examines SM burden from both patient and provider perspectives

  A first-of-its-kind study in Europe identified sources of disease burden as reported by patients with SM and their healthcare providers.

• Sarilumab does not improve quality of life in patients with indolent SM

  A clinical trial of 16 patients with indolent SM found that sarilumab does not significantly improve quality of life.

• Case report: Patient diagnosed with rare, aggressive form of SM

  A patient who was diagnosed with mast cell leukemia, a rare form of SM, experienced symptom relief with methylprednisolone treatment.

• Case report: Patient develops SM after germ cell tumor treatment

  A 9-year-old girl underwent a stem cell transplant after being diagnosed with SM following treatment for a germ cell tumor.

• Case report: Aortic valve replacement failure in patient with aggressive SM

  A case report describes a patient who experienced two failed transcatheter aortic valve replacements, likely related to her underlying SM.