Features

Experts consistently emphasize: when in doubt, use epinephrine.

Abnormal and overactive mast cells can accumulate in many different areas of the body, including the lungs. 

Mast cell activation causes tryptase to be released into the bloodstream, raising serum tryptase counts. 

The KIT D816V mutation almost always develops during a person’s lifetime, rather than being inherited.

A CT scan is painless and only takes a few minutes.

Chemicals released by mast cells can affect body temperature regulation, leading to flushing and sweating.

While both forms involve abnormal mast cells, nonadvanced and advanced SM behave very differently.

The histamine bucket theory is a simple visual aid that shows how histamine builds up in the body.

The primary method of managing urticaria pigmentosa involves avoiding your triggers.

Whether it’s a weekly tidy or a deep spring clean, it’s important to plan ahead.