Ariana Boswell

All articles by Ariana Boswell

• Avapritinib may alleviate skin symptoms in patients with indolent SM long-term

  Patients with indolent SM who took avapritinib saw significant improvements in itching, flushing and skin spots that lasted for three years.

• Patients with SM may experience cardiovascular symptoms

  Individuals with mast cell diseases like SM may experience cardiac, vascular and bleeding symptoms that need specialized care.

• Combining genetic and blood testing may improve SM diagnosis

  Researchers developed an algorithm that helps differentiate SM from hereditary alpha-tryptasemia, a condition with many overlapping symptoms.

• What is KIT D816V mutation testing?

  KIT D816V mutation testing is simple – all it takes is a blood draw.

• Case report: Severe SM and KIT mutation in an infant

  This study represents the first known case of a patient with SM with detectable KIT D816V mutations in all cells of the body.

• Mastocytosis and Mast Cell Diseases Awareness Day 2025: How to get involved

  October 20 is International Mastocytosis and Mast Cell Diseases Awareness Day, a day dedicated to showing support and building community.

• Case report: Patient presents with KIT-negative SM and acute myeloid leukemia

  The case highlights the challenges of diagnosing and treating both KIT-negative SM and SM with an associated hematologic neoplasm (SM-AHN).

• Blood genetic testing alone may miss cases of SM

  Patients who test negative for the KIT D816V mutation may need further testing for clonal mast cell diseases such as SM, a study found.

• What is the WHO classification for systemic mastocytosis subtypes?

  The WHO guidelines provide a standardized framework that helps doctors provide the right care for patients.

• New test may improve detection of KIT mutations

  Flow-SuperRCA is a new, ultra-sensitive test to detect the D816V KIT mutation in patients with SM and other mast cell conditions.