Oct. 20, 2025, marks the eighth annual International Mastocytosis and Mast Cell Diseases Awareness Day. On this day, patients with systemic mastocytosis (SM) and other mast cellMast cell A type of white blood cell produced in the bone marrow. They help defend against infections and play a key role in allergic reactions. In SM, mast cells become overactive and build up throughout the body. conditions will connect with physicians and researchers to share their stories and advocate for change.
The MastocytosisMastocytosis Rare disease caused by the buildup of mast cells. Cutaneous mastocytosis primarily affects the skin and is more common in children, while systemic mastocytosis affects internal organs and is more common in adults. and Mast Cell Diseases International Committee was created in 2018 by 23 organizations across 21 nations with the goal of improving communication between patients and the doctors and researchers who study these diseases.
This year, the campaign’s slogan is “Be informed, be connected.” This theme promotes not only engagement with experts and patient organizations, but also improved education surrounding mast cell diseases.
There are many ways to show your support on International Mastocytosis and Mast Cell Diseases Awareness Day. If you live in the United States, you can encourage your governor to proclaim October 20 as Mast Cell DiseaseMast cell disease A group of conditions in which mast cells behave abnormally by building up in excess, releasing chemicals too easily or both. Includes mastocytosis, mast cell activation syndrome and hereditary alpha-tryptasemia. Awareness Day. Some states that have already done so include Pennsylvania, North Carolina and Tennessee.
Read more about helpful links and resources for SM
Landmarks throughout the world will also light up purple, the official campaign color, to commemorate the day. The color represents the purple dye that researchers use in the lab to visualize mast cells. In past years, buildings across several continents have participated.
Social media is an easy way to get involved as well. The committee provides logos and ribbons in many languages to download and share online. Patients can share their personal stories alongside these visuals to help spread awareness. Individuals can also host social media fundraisers to help raise money for improved mast cell research.
Participating in-person is as easy as wearing a purple ribbon with white polka dots, which represent the hives and rashes that patients often experience. This small accessory can serve as a simple conversation starter and symbol of solidarity.
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