Leonardo Jaimes, MD

All articles by Leonardo Jaimes, MD

• Case report: SM manifesting as back pain

  The clinical manifestations of SM vary greatly from patient to patient, with some presenting back pain as an isolated symptom.

• Case report examines seizures as a systemic mastocytosis manifestation

  A rare case of systemic mastocytosis (SM) manifesting as generalized seizures was recently described in a case report.

• Non-white systemic mastocytosis patients wait longer for diagnosis

  Non-white patients with systemic mastocytosis appear to have a longer diagnostic journey and a greater disease burden than white patients.

• Indolent SM subtype associated with high disease burden

  Though patients with ISM have a normal life expectancy, they need more health care visits and medications than the general population.

• Keys to SM diagnosis in patients with low circulating KIT D816V

  While present in most cases of SM, KIT D816V is not the only diagnostic marker of the disease.

• Case study provides insights into mast cell leukemia

  A recent case report provides insight on the management of mast cell leukemia (MCL), a rare systemic mastocytosis (SM) subtype.

• Case study highlights osteoporosis as a sign of SM

  Osteoporosis can be the presenting manifestation of systemic mastocytosis (SM), according to a recent case report.

• Child had SM even though he had no classic symptoms, case report says

  A child was eventually diagnosed with systemic mastocytosis (SM) though he presented with none of the usual systemic symptoms.

• Patients who don’t meet all WHO criteria for SM can have same symptoms

  Patients with bone marrow mast cell infiltration who do not meet WHO criteria for SM can still have symptoms and are at risk for osteoporosis.

• Study underscores need for regular monitoring after indolent SM diagnosis

  A hematologist detailed several cases of SM that highlighted the need for diligence in diagnosing and managing treatment of ISM.