Leonardo Jaimes, MD

All articles by Leonardo Jaimes, MD

• Phase 2 trial of bezuclastinib for SM partially completed

  The phase 2 Apex trial aiming to test bezuclastinib in patients with SM, has recently completed enrollment for part one of the trial.

• Study shows link between Hymenoptera venom allergy and CMD

  A recently published study showed those with Hymenoptera venom allergy (HVA) should be screened for clonal mast cell diseases (CMD).

• Study: Specialists lack knowledge, awareness of systemic mastocytosis

  According to a recently-published article, increased knowledge and awareness of systemic mastocytosis is needed among specialists.

• Case study: SM diagnosed through CT and PET scans

  A patient was diagnosed with aggressive SM due to findings from computerized tomography (CT) and contrast-enhanced PET scans.

• Patient diagnosed with mast cell leukemia, the rarest form of SM

  A recent case report details a patient with mast cell leukemia (MCL), which authors state may be the rarest form of systemic mastocytosis (SM).

• Case report: SM patient successfully treated for osteoporosis

  A case of patient with osteoporosis and systemic mastocytosis (SM) has highlighted the treatments available and the need for more data.

• New study explains how systemic mastocytosis can affect the liver

  The cellular changes that occur in the liver of patients with systemic mastocytosis (SM) have been described in a recent study.

• Systemic mastocytosis presents challenges during heart surgery

  A recent report describes a patient with undiagnosed systemic mastocytosis who experienced unexpected complications during heart surgery.

• Case report: 2 patients without KIT mutations diagnosed with SM

  Two cases involving patients with systemic mastocytosis (SM) without KIT mutations (KIT negative) have been recently reported.

• Desensitization to isatuximab allergy possible in patients with ISM

  Desensitization to isatuximab allergy in patients with ISM appears possible, according to a recent report.