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For most people with SM the benefits of vaccination outweigh any risks when appropriate precautions are taken.

With time, self-compassion and support, it’s possible to build confidence and start feeling more comfortable in your own skin.

The Darier’s sign is not a definitive test for SM, but it’s one of many tests that doctors may use to help get closer to a diagnosis.

Experts consistently emphasize: when in doubt, use epinephrine.

Abnormal and overactive mast cells can accumulate in many different areas of the body, including the lungs. 

Mast cell activation causes tryptase to be released into the bloodstream, raising serum tryptase counts. 

The KIT D816V mutation almost always develops during a person’s lifetime, rather than being inherited.

A CT scan is painless and only takes a few minutes.

Chemicals released by mast cells can affect body temperature regulation, leading to flushing and sweating.

While both forms involve abnormal mast cells, nonadvanced and advanced SM behave very differently.