Patient outcomes in MCL remain poor despite therapeutic advancements
Outcomes among patients with mast cell leukemia remain relatively poor.
News
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Case report: New KIT mutation identified in a patient with SM
A case report was recently published describing a man with systemic mastocytosis and a previously unknown KIT mutation.
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SM treatment has improved, but more therapies are needed for rare subtypes
Major progress has been made in the treatment of SM, but patients with the most aggressive forms of the disease still need better options.
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Researchers highlight complex mutational profile of SM-AHN
Systemic mastocytosis with an associated hematologic neoplasm (SM-AHN) appears to have a higher mutational burden than isolated SM.
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People with SM may face higher risk of skin cancer, study finds
People with mastocytosis may have an elevated risk of melanoma and basal cell carcinoma compared to the general population.
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Review explores how genetic advances are reshaping SM diagnosis and treatment
A new review underscores how genetic research is transforming the diagnosis and management of systemic mastocytosis.
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Case report: Patient diagnosed with both SM and POTS
A rare presentation of systemic mastocytosis (SM) alongside postural orthostatic tachycardia syndrome (POTS) was recently reported.
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Study highlights the diagnostic challenges of SM-AMN
A new study explores the diagnostic challenges posed by SM with an associated myeloid neoplasm (SM-AMN), an advanced form of SM.
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Research suggests midostaurin is still effective at lower doses in advanced SM
Midostaurin is safe and effective in treating advanced systemic mastocytosis.
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Rare case of aggressive systemic mastocytosis identified in newborn
A new case study from New Zealand sheds light on diagnostic and treatment challenges for aggressive systemic mastocytosis in newborns
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